The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias

Lavallée VP, Baccelli I, Krosl J, Wilhelm B, Barabé F, Gendron P, Boucher G, Lemieux S, Marinier A, Meloche S, Hébert J, Sauvageau G.
The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias.
Nature Genetics (2015), 47(9):1030-7.

E4F1 is a master regulator of CHK1-mediated functions.

Grote D, Moison C, Duhamel S, Chagraoui J, Girard S, Yang J, Mayotte N, Coulombe Y, Masson JY, Brown GW, Meloche S, Sauvageau G.
E4F1 is a master regulator of CHK1-mediated functions.
Cell Reports (2015), 11(2):210-9.

Haploinsufficiency screen highlights two distinct groups of ribosomal protein genes essential for embryonic stem cell fate.

Fortier S, MacRae T, Bilodeau M, Sargeant T, Sauvageau G.
Haploinsufficiency screen highlights two distinct groups of ribosomal protein genes essential for embryonic stem cell fate.
PNAS USA (2015), 112(7):2127-32.